Below are links to and brief summaries of public use data, resources, and tools available through the NIH.
- Cancer Genetics Network
The Cancer Genetics Network (CGN) is a resource for investigators conducting research on the genetic basis of human cancer susceptibility; integration of this information into medical practice; and behavioral, ethical, and public health issues associated with human genetics. The CGN can provide a wide variety of research services and specialized expertise to assist investigators with approved studies. Prospective investigators can freely query the CGN core database to learn more about the aggregate characteristics of participants and discover how the CGN may be used for research purposes.
- NIDA Data Share Website
The National Institute on Drug Abuse (NIDA) Data Share site provides access to de-identified data from completed clinical trials to promote new research, encourage further analyses, and disseminate information to the community.
The National Library of Medicine maintains a database of Genotypes and Phenotypes (dbGaP), developed to archive and distribute the results of studies that have investigated the interaction of genotype and phenotype. Among its collection of studies, dbGaP includes data from the Collaborative Genetics of Alcoholism (COGA) project, where family members, including adults, children, and adolescents, have been carefully characterized across a variety of domains, including alcohol and other substance-related phenotypes and co-occurring disorders (e.g., depression).
- Genetics Data Harmonization Project
NIDA's Genetic Consortium has created a list of domains and their associated measures to help with the harmonization of data in genetics research.
- Grid-Enabled Measures
Grid-Enabled Measures (GEM) is a dynamic web-based database that contains behavioral and social science measures organized by theoretical constructs. GEM is designed to enable researchers to use common measures with the goal of exchanging harmonized data. Through the use of these standardized measures and common elements, prospective meta-analyses will be possible.
- HIV Research Common Measures
A set of measures has been developed as part of NIDA’s Seek, Test, Treat and Retain Initiative in order to increase the comparability, collaboration, and scientific yield of clinical research on HIV and substance abuse.
- National Addiction & HIV Data Archive Program (NAHDAP)
NAHDAP acquires, preserves and disseminates data relevant to drug addiction and HIV research. By preserving and making available an easily accessible library of electronic data on drug addiction and HIV infection in the United States, NAHDAP offers scholars the opportunity to conduct secondary analysis on major issues of social and behavioral sciences and public policy
- National Epidemiologic Survey on Alcohol and Related Conditions
The National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) was designed to determine the prevalence and patterns over time of alcohol use disorders and their associated disabilities (e.g., depression, anxiety, etc) in the general population and in specific subgroups. NESARC also contains data on other drugs of abuse and smoking, independent of alcohol, including drug use disorders.
- Neuroscience Information Framework
A dynamic inventory of Web-based neuroscience resources such as data, materials, and tools accessible which advances neuroscience research by enabling discovery and access to public research data and tools worldwide through an open source, networked environment.
- NIDA Drug Supply Program
The NIDA Drug Supply Program, administered by the Chemistry & Physiological Systems Research Branch at NIDA, facilitates research by providing researchers chemicals and research probes that are either unavailable, difficult to obtain, or very expensive to buy. In addition, this program also provides analytical services of experimental samples.
- NIH Toolbox
The NIH Toolbox is a multidimensional set of brief measures assessing cognitive, emotional, motor, and sensory functions from ages 3 to 85, meeting the need for a standard set of measures that can be used as a “common currency” across diverse study designs and settings.
- PhenX Toolkit
Consensus measures for phenotypes and exposures--this includes a collection of standardized measures related to substance abuse and addiction. The project is led by RTI International and funded by the National Human Genome Research Institute (NHGRI). NIDA recommends that all addiction researchers incorporate these standard measures into their human-subjects research, thereby facilitating the gathering and sharing of interoperable data in the addiction sciences.
- Tobacco Use Supplement to the Current Population Survey
The Tobacco Use Supplement to the Current Population Survey (TUS-CPS) is an NCI-sponsored survey of tobacco use and policy information that has been administered as part of the U.S. Census Bureau's Current Population Survey since 1992. The TUS-CPS is a key source of national, state, and sub-state level data on smoking and other tobacco use in U.S. households. These data can be used by researchers to monitor progress in the control of tobacco use, conduct tobacco-related research, and evaluate tobacco control programs.
- WHO guidelines for identification and management of substance use and substance use disorders in pregnancy
Tobacco use and second-hand smoke (SHS) exposure during pregnancy have numerous adverse health effects for women and infants. The potential for increased tobacco use and SHS exposure among pregnant women threaten to undermine hard-won gains in maternal and children health outcomes. The World Health Organization, with funding and technical support from the U.S. Centers for Disease Control and Prevention and the U.S. National Cancer Institute, has provided guidelines to reduce tobacco use and SHS exposure in pregnant women, by providing evidence-based recommendations to health care professionals involved in the care and treatment of pregnant women, as well as public health policy-makers, program managers, and others.
- WHO recommendations for the prevention and management of tobacco use and second-hand smoke exposure in pregnancy
The use of alcohol, illicit drugs, and other psychoactive substances during pregnancy can lead to multiple health and social problems for both mother and child. Use of alcohol during pregnancy can lead to fetal alcohol syndrome and other fetal alcohol spectrum disorders in addition to other harms such as spontaneous abortion, stillbirth, low birthweight, and prematurity. Dependence on alcohol and other drugs can also severely impair an individual’s functioning as a parent, spouse, or partner. Pregnancy may present an important opportunity for women, their partners, and other people living in their households to change their patterns of alcohol and other substance use. These guidelines have been developed to enable professionals to assist women who are pregnant, or have recently given birth and who use alcohol or other drugs, or who have a substance use disorder to achieve healthy outcomes for themselves and their families. Technical support was provided by the National Institute on Alcohol Abuse and Alcoholism and the National Institute on Drug Abuse.